| Session 1. Optimization of Drug Delivery Efficiency |
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A major challenge to pharmaceutical scientists in new drug development is in the optimization of drug delivery properties to improve the therapeutic effectiveness of drugs. Many studies have supported that poor pharmacokinetic properties heavily contribute to compound failure or at a minimum, difficulty of the compound to progress through drug development. Therefore, in this session, several case studies are illustrated to enlighten the current approaches for improving oral drug delivery efficiency and ultimately for maximizing the therapeutic benefits of drugs. |
| Chair : In Koo CHUN, Professor, Dongduk Women's Univ. |
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- Delivery of Drugs to Target Tissues
: Project Supports and BBB Initiative in Drug Discovery |
| Dooman OH, Associate Director, Clinical Pharmacology, PPD Inc. |
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- Microenvironmental pH and Crystal Behavior of Ionizable Drug by
Alkalizers in Solid Dispersions |
| Beom-Jin LEE, Professor, College of Pharmacy, Kangwon Nat’l Univ. |
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- Preparation of Cyclosporine A Lipid Emulsion Using Membrane
Emulsification Method |
| Eun-Seok PARK, Professor, College of Pharmacy, Sungkyunkwan Univ. |
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| Session 2. Disease-Oriented Drug Delivery |
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Efficient drug delivery to target tissue is prerequisite for disease control by chemotherapy. Target tissue characteristics should be taken into consideration in strategy development for effective drug delivery and maximum drug efficacy. Solid tumors represent a particular interest in term of unique histophysiology and intrinsic chemo-resistance, which makes it important to develop selective drug delivery systems and to study pharmacokinetics in avascular region of solid tumors. This session will focus on recent research trends regarding vascular and avascular delivery of anticancer drugs using novel drug delivery systems or 3-dimensional cell culture models. |
| Chair : Hyo Kyung HAN, Professor, Chosun Univ. |
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- Tumor Priming to Promote Nano- and Micro-particle Delivery to
Solid Tumors |
| Jessie L.S. AU, Distinguished Univ. Professor, College of Pharmacy, The Ohio State Univ. |
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- Drug Delivery and Activity in Solid Tumors
: A Pharmacokinetic Perspective |
| Hyo-Jeong KUH, Associate Professor, College of Medicine, The Catholic Univ. of Korea |
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| - Targeted Drug Delivery via Surface-modified Nanoparticles |
| Chang-Koo SHIM, Professor, College of Pharmacy, Seoul Nat’l Univ. |
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| Session 3. Advances in Drug Delivery Technology |
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| Development of novel technology of drug delivery system might be more efficient compared with conventional novel synthetic drug in terms of the invest money and duration, especially Korea which is coupled with Korea-USA FTA and inferior basement of discovery of new drug. Also, developed novel DDS technology can be applied to several drugs and various symptoms that is platform technology. In this session, we will discuss profoundly for the nanobiomaterials for tissue engineering and drug delivery, nucleic acid delivery using nanotechnology and micro needle system for macromolecular drug. |
Chair : Beom Jin LEE, Professor, Kangwon Nat'l Univ. |
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- Peptide Based Nanobiomaterials for Drug Delivery and
Tissue Engineering Purpose
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| Yoon Jeong PARK, Assistant Professor, School of Dentistry, Seoul Nat’l Univ. |
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| - Delivery of Nucleic Acid-Based Medicines Using Nanotechnology |
| Yu-Kyoung OH, Associate Professor, School of Life Sciences and Biotechnology, Korea Univ. |
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| - Recent Advances on Microneedle System for Drug Delivery |
| Gilson KHANG, Professor, Dept of PolymerNano Sci. & Tech., Chonbuk Nat’l Univ. |
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